In controlled studies, PERIDAN® Concentrate has…

Shown to be safe in an equine clinical model with:

  • No septic peritonitis in a clean-contaminated model
  • No affect on mechanical strength of anastomosis
  • No affect on incision infection rate

Shown to be effective when administered intraperitoneally in an equine jejunal abrasion model with:

  • A 65% reduction in the number of adhesions
  • A 76% decrease in the severity of adhesions
  • Demonstrated favorable long-term outcome with regard to survival and colic
    • Short-term survival 94%
    • 84% of horses show no signs of colic
    • Short-term survival rate of 31/33 (94%)
    • Long-term survival rate* of 29/31 (94%)

References

S. Morello, L. L. Southwood, J. Slack, A Crack and C. M. K. Springate. Safety of intraperitoneal fucoidan solution in healthy adult horses undergoing exploratory celiotomy and jejunojejunostomy: Clinical findings. Presented at the American College of Veterinary Surgeons Symposium, Washington – October 2009.

S. Morello, L. L. Southwood, J. Engiles, A Crack and C. M. K. Springate. Safety of intraperitoneal fucoidan solution in healthy adult horses undergoing exploratory celiotomy and jejunojejunostomy: post-mortem findings. Presented at the American College of Veterinary Surgeons Symposium, Washington – October 2009.

S. Yamout. Effects of 0.03% Fucoidan Instillate on Prevention of Experimentally Induced Abdominal Adhesions in Pony Foals. Presented at the American College of Veterinary Surgeons’ Symposium, Chicago – October 2007.

S. Yamout, L. P. Bouré, C. Theoret, C. M. K. Springate, A Crack, S. Weese, S Nykamp, K. Woods and A. Hathway. Effects of 0.03% weight/volume fucoidan solution on the prevention of experimentally induced abdominal adhesions in healthy pony foals. Presented at the European College of Veterinary Surgeons’ Scientific Symposium, Dublin – June 2007.